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Substance P
Cat. No. NR-140
Structure:
Other Names:
Activity:
Andoh et al (1998) Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J.Pharmacol.Exp.Ther. 286 1140 PMID: 9732370
Walsh et al (1995) Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists and the role of endogenous mediators. Br.J.Pharmacol. 114 1343 PMID: 7541689
Zieglgänsberger (2019) Substance P and pain chronicity. Cell Tissue Res. 375(1) 227 PMID: 30284083
Related Areas
All peptides >
All tachykinin receptor modulators >
All pain research categories >
All neuroscience research categories >
All immunology research categories >
Technical Data
Structure | H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
CAS Number | 33507-63-0 |
Molecular Weight | 1347.6 |
Formula | C63H98N18O13S |
Sequence | RPKPQQFFGLM-NH2 |
Modifications | C terminal amide |
Solubility and Storage
Solubility | Soluble in dilute acid and physiological buffers |
Appearance | Freeze dried solid |
Storage | We recommend storage desiccated, frozen and in the dark |
Batch Specific Data
Purity | >95% by HPLC |
Certificate of Analysis | Substance P PRN0628-200504 Product Datasheet_602d0ba9db326.pdf |
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Recent citations
A new publication from the University of Ljubljana uses MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2, the FRET substrate for the severe acute respiratory syndrome coronavirus main protease (SARS-CoV Mpro), to determine the inhibitory potential of plant polyphenols
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