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Crosstide

Cat. No. KS-070

Structure:

H-Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly-OH

Activity:

Akt/PKB (protein kinase B) substrate 
Price Qty
1 mg    $ 79.00
Crosstide is a synthetic peptide derived from glycogen synthase kinase-3β (GSK-3). Crosstide functions as substrate for Akt/PKB (protein kinase B) and is also recognized by MAPKAP kinase-1 and p70S6K, Crosstide also displays similar selectivity towards PKBα, PKBβ and PKBγ isoforms. The fluorescent and biotinylated versions of crosstide demonstrate similar enzymic activity.

Dai (2002) Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta (GSK-3β) at serine-9 through direct interaction Biochem. Biophys. Res. Comm. 293 (4) 1191 PMID: 12054501

Baer et al (2005) Activation of a GST-tagged AKT2/PKBbeta. Biochim. Biophys. Acta 1725(3) 340 PMID: 15890450

Xu et al (2005) WNK1 Activates SGK1 by a Phosphatidylinositol 3-Kinase-dependent and Non-catalytic Mechanism. J. Biol. Chem. 280 34218 PMID: 16081417


Related areas

All kinase modulators >
All substrate peptides >


Technical Data

Structure H-Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly-OH
CAS Number 171783-05-4
Molecular Weight 1165.2
Formula C48H77N17O17
Sequence GRPRTSSFAEG
Modifications None

Solubility and Storage

Solubility Soluble in dilute acid
Appearance Freeze dried solid
Storage Store dark, frozen and desiccated

Batch Specific Data

Purity >95% by HPLC
Safety Data Sheet Crosstide MSDS_602bacf4eedd4.pdf

Contact Information

To place an order, or for customer services, order processing or technical support please contact us on:

UK, Europe and RoW
Tel: (+44) 01392 422205
Fax: (+44) 01392 279510
info@iscabiochemicals.com

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Tel: 610-994-1134

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France

CliniSciences
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Fax :  +33 9 77 40 10 11
Orders and customer support : info@clinisciences.com


Germany, Switzerland, Austria

BIOZOL Diagnostics 

Tel: +49 (089) 3799 666-6

Fax: +49 (089) 3799 666-99
Orders, Technical and Customer support: info@biozol.de


Italy
Labospace
Tel: +39 02 35980841
Fax +39 02 359808004
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Spain and Portugal
Abyntek Biopharma
Tel: +34 94 404 80 80

Fax: +34 94 404 80 81
Orders: info@abyntek.com


China

BIOHUB INTERNATIONAL 

上海起发实验试剂有限公司

Tel: +86-15921799099

Tel: +86-021-50724187

Fax: +86-021-50724961

Orders: sale3@78bio.com

India
BTL Biotechno Labs Pvt Ltd
Tel: +91-8860924629
07291852429
Orders, Technical and Customer support: info@biotechnolabs.com


Japan

Namiki Shoji Co.
Tel:+81-050-5527-9850
Fax:+81-3-3352-2196
email:  globalbusiness1@namiki-s.co.jp


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