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(NLysNpheNphe)2-NH2

Cat. No. PT-103

Structure:

NLys-Nphe-Nphe-NLys-Nphe-Nphe-NH2

Activity:

Antibacterial and antiparasitic
Price Qty
1 mg    $ 165.00
Peptoids are peptide-mimicking poly-N-substituted glycines, which exhibit enhanced physiological stability and are known to have antibacterial and antiparasitic qualities. They have recently been shown to have activity against Leishmania mexicana axenic amastigotes. NLys is the N-(4-aminobutyl)glycine peptoid monomer and Nphe is the N-(phenylmethyl)glycine peptoid monomer

Chongsiriwatana et al (2008) Peptoids that mimic the structure, function, and mechanism of helical antimicrobial peptides. Proc. Natl. Acad. Sci 105(8) 2794 DOI: 10.1073/pnas.0708254105

Zuckermann (2011) Peptoid origins. Biopolymers, 96 545 doi:10.1002/bip.21573

Sun and Zuckermann (2013) Peptoid Polymers: A Highly Designable Bioinspired Material. ACS Nano 7(6) 4715 https://doi.org/10.1021/nn4015714

Huang et al (2014) Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity. PLoS ONE 9(2) e90397. https://doi.org/10.1371/journal.pone.0090397

Eggimann et al (2015) Investigating the Anti‐leishmanial Effects of Linear Peptoids. ChemMedChem. 10 233 doi:10.1002/cmdc.201402416


Related areas

All peptoids >
All antibacterials >


Technical Data

Structure NLys-Nphe-Nphe-NLys-Nphe-Nphe-NH2
Molecular Weight 862.1
Formula C48H63N9O6
Sequence NLys-Nphe-Nphe-NLys-Nphe-Nphe-NH2
Modifications NLys is the N-(4-aminobutyl)glycine peptoid monomer and Nphe is the N-(phenylmethyl)glycine peptoid monomer For more information about peptoids and their nomenclature please refer to the peptide resources page

Solubility and Storage

Solubility Soluble in dilute acid
Appearance Freeze dried solid
Storage Store desiccated, frozen and in the dark

Batch Specific Data

Purity >90% by HPLC

Contact Information

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