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Latest News

External peptide resources

Published on April 7th 2021

We needed a place to find our favourite peptide resources links so we have collected up the following pages in one place as external peptide resourcesand we hope that people will find it as useful as we do. Please let us have any suggestions for any other peptide resourcesthat should be here.ProtParamcan determine physical and chemical parameters for a given protein in Swiss-Prot or TrEMBL or for a user entered sequence. Parameters include molecular weight, theoretical pI, amino acid composition...


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New synuclein knockdown peptide

Published on March 5th 2021

Tat-βsyn-degronis a blood brain barrier and plasma membrane permeable α-synuclein knockdown peptide which can reducethe level of α-synuclein byproteasomal degradation. Tat-βsyn-degron decreasesα-synuclein aggregates and microglial activation in an α-synuclein preformed fibril model of spreading synucleinopathy in transgenic mice overexpressing human A53T α-synuclein, and reducesα-synuclein levels and significantly decreasesthe neuronal damage and motor impairment in a mouse toxicity mode...


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New website launched

Published on March 4th 2021

We are pleased to say that our new website went live today. It is designed to be as informative and user friendly as possible, withproducts are now grouped for browsing by pharmacology, product type or research application for easy identification. The new search facility allows searches by product name, or partial name, sequence, or partial sequence, andCAS number. We have added a section of external peptide links and ordering online has been introduced and the process greatly simplified. We hop...


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Free catalogue peptide shipping in March

Published on March 1st 2021

Free catalogue peptide shipping is extended into Marchfor all UK and European customers. Please quote Mar2021 on your order...


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New citations for LL 37 and Parasin I

Published on December 3rd 2020

Antimicrobial peptides, or host defence peptides, are active against bacteria, viruses, microscopic fungi and protozoa. Two new publications, from the University of Leipzig and the University of Helsinki have recently made use of LL 37, the host defence peptide derived from the human cathelicidin antimicrobial peptide hCAP18, and Parasin I, the amphipathic antimicrobial peptide derived from histone H2A of the catfish. The Leipzig group have show the activity of both peptides against periodonta...


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Novel peptidomimetic probes for NTMT1/2

Published on September 22nd 2020

Protein N-terminal methyltransferases (NTMTs) methylate the α-N-terminal amines of proteins starting with the canonical X-P-K/R motif. Genetic studies imply that NTMT1 regulates cell mitosis and DNA damage repair. Isca Biochemicals are pleased to announce the availability of first potent peptidomimetic inhibitors for NTMT1/2, BM30, a competitive inhibitor to the peptide substrate but noncompetitive to the cofactor S-adenosylmethionine, and the analogue DC432 which is BM30 made cell permeable ...


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New range of pain regulatory peptides

Published on September 10th 2020

Isca Biochemicals is pleased to announce that a new range of pain regulatory peptides is now available. Our new range contains a mixture of research standards and exclusive peptides that act on established pain targets such as neurokinin 1 (NK1), bradykinin (B1 and B2),the nociceptin receptor (NOP, ORL-1),inward rectifier K+ channels,sensory neuron specific receptors (SNSRs), connexin43 hemichannels,transient receptor potential ion channels TRPA1 and TRPV1, the interaction of the axonal collapsi...


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New appetite regulatory peptides available

Published on August 14th 2020

Ghrelin (rat) (GH-180) and ghrelin (human) (GH-190), the endogenous agonists for the rat and human ghrelin receptors are now available from Isca Biochemicals. Ghrelin is produced by the stomach, and is linked to inducing appetite and feeding behaviour, and is a key component of the appetite control sytem that originates from the hypothalamus. In addition to these new ghrelins, Isca Biochemicals offers a range of appetite regulatory peptides acting on the key components of the appetite control sy...


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Contact Information

To place an order, or for customer services, order processing or technical support please contact us on:

Tel: (+44) 01392 422205

Fax: (+44) 01392 279510


[email protected]